Tracer Science Is All We Do
30+ years of exclusive stable isotope specialization, including 2H, 13C, and 18O methods that uncover pathways other labs can’t measure.
Faster Timelines Without Cutting Corners
Metabolism-focused operations mean protocol consults and regulatory-ready reports delivered weeks faster than generalist CROs.
Data Regulators Already Trust
GLP-compliant, CLIA-certified, and 21 CFR Part 11 validated — ensuring reproducible, inspection-ready data accepted by FDA and EMA.
Your Scientific Partner, Not Just a Vendor
From study design to interpretation, our scientists work as an extension of your team to ensure every tracer protocol answers your therapeutic question.
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Dan T.
CAMP4
De Novo Lipogenesis
Quantify DNL, lipolysis, fatty acid turnover, oxidation, and glycerol kinetics using 13C and deuterium tracers. Reveal dynamic lipid flux and mechanistic drivers of metabolic disease.
Muscle Protein Turnover
Quantify muscle protein synthesis, turnover rates, and protein half-lives using D₂O and amino acid tracer methods. Obtain dynamic, reproducible muscle remodeling endpoints.
Glucose Kinetics
Quantify hepatic glucose production, disposal rates, oxidation, gluconeogenesis, and whole-body glucose flux using validated 13C and deuterium tracers. Generate precise, regulator-ready glucose metabolism endpoints.
Energy Expenditure
Measure total daily energy expenditure in humans and animals using the validated doubly labeled water (DLW) method. Obtain accurate, non-invasive energy expenditure data
Total Body Water
Measure total body water and extracellular fluid volume using validated D₂O, 18O, and NaBr tracer methods. Obtain accurate, reproducible body water compartment data from minimal sample volumes.
Amino Acid Metabolism Analysis
Quantify amino acid kinetics, oxidation, transamination, and metabolic fate using 13C and 15N tracer assays. Reveal dynamic amino acid metabolism and therapeutic effects.
Breath Test Endpoints
Non-invasive 13C- and gas-based assays that quantify liver, gastric, pancreatic, and GI function with regulator-trusted precision. Measure enzyme activity, organ function, and digestive health in real time.
Fibrosis & Collagen Turnover
Measure new collagen synthesis in vivo using deuterium or 13C tracers to quantify fibrosis activity with high sensitivity. Detect early antifibrotic effects with collagen synthesis assays that provide dynamic, regulator-trusted endpoints.
Oncology: Cell Proliferation
Quantify in vivo DNA synthesis and cellular growth by measuring deoxyribose enrichment after D₂O labeling. Obtain sensitive, reproducible proliferation endpoints.
Targeted Protein Half-Life
Quantify in vivo protein synthesis, degradation, and half-life using D₂O-based isotopic labeling and mass spectrometry. Generate dynamic, pathway-independent protein turnover endpoints.
Urea Cycle Disorder
Quantify urea cycle capacity and compensatory ammonia-detoxification pathways using 13C and 15N tracers. Obtain pathway-specific, clinical-grade functional endpoints for UCD programs, supporting gene therapy, RNA therapeutics, and dose-response evaluation.
Rare Disease & Gene Therapy
Measure in vivo enzyme activity for disorders such as PKU and MMA using 13C- and 15N-based breath and plasma tracer assays. Generate sensitive, reproducible, regulator-trusted efficacy endpoints with patient-friendly stable isotope protocols
End-Product Nitrogen Metabolism
Measure ammonia handling, ureagenesis, amino acid metabolites, and nitrate synthesis using 15N and 13C tracers. Map whole-pathway nitrogen metabolism with reproducible tracer-based endpoints for metabolic, probiotic, and amino acid disorder research.
Metabolic Solutions, LLC.
460 Amherst St., Nashua,
NH 03063, USA
Fax: (603) 598-6973
Hours of Operation
Monday – Friday
7:30 am – 6:00 pm EST
