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    GI Breath Tests

    Validated Hydrogen, Methane, and Urea Breath Testing

    We make it easy for healthcare providers to offer GI breath testing by providing complete test kits and laboratory analysis services. Patients can test at home or in-office, and we handle the rest.

    Accurate, lab-analyzed results, delivered in just days.

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    As a provider, which of these best describes you?

    • I’m looking to place my first order

    • I’m looking for more information on your tests

    • I’m looking to order additional kits

    Trusted by The Most Respected Healthcare Institutions

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    Precision Breath Testing, Backed by Decades of Metabolic Research

    Why Gastroenterologists, Internists, And Functional Medicine Practitioners Trust Our Breath Tests

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    Focused Expertise

    Breath testing is our sole focus—no other lab matches our depth of experience.

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    Fast Results 

    No clinic visits. Results analyzed and delivered in just days—not weeks.

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    Best-in-Class Analysis

    Hydrogen and methane measured by gas chromatography—the same technology used in major medical centers.

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    Certified & Reliable

    CLIA-certified independent clinical laboratory, licensed in all 50 states.

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    The Importance of Breath Testing

    Why Partner With
    Metabolic Solutions

    For over 35 years, Metabolic Solutions has advanced the science of metabolic isotope and breath testing for clinical and pharmaceutical research.

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    circle-checkProven record of scientific precision and operational reliability.
    headphonesDedicated provider support team for seamless integration.

    Available Diagnostic Breath Tests

    Each GI breath test kit includes all materials for in-office or at-home collection, plus a prepaid mailer for returning samples to our CLIA-certified lab. Reports are faxed or emailed within 24 hours of receipt.

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    Small intestinal Bacterial Overgrowth (SIBO) - Glucose Breath Test

    Hydrogen/methane breath test using glucose solution with timed collections (0, 30, 60, 90 min). It identifies bacterial overgrowth in the small intestine associated with bloating, diarrhea, and IBS-like symptoms.

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    Small intestinal Bacterial Overgrowth (SIBO) - Lactulose Breath Test

    Hydrogen/methane breath test using lactulose challenge with timed collections (0, 30, 60, 90 min). It identifies bacterial overgrowth in the small intestine associated with bloating, diarrhea, and IBS-like symptoms.

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    Lactose Intolerance Breath Test

    Timed hydrogen/methane breath test after 25g lactose ingestion. It assesses your patient’s ability to digest lactose and helps confirm dietary intolerance to milk and dairy products.

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    13C-Sucrose Intolerance
    Breath Test

    Timed 13CO2 breath test after 20 g sucrose ingestion. It determines whether insufficient sucrase activity is contributing to gas, bloating, or abdominal discomfort.

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    Fructose Malabsorption
    Breath Test

    Timed hydrogen/methane breath test after 25 g fructose ingestion. It determines whether unabsorbed fructose is contributing to gas, bloating, or abdominal discomfort.

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    H2-Sucrose Intolerance
    Breath Test

    Timed hydrogen/methane breath test after 50 g sucrose ingestion. It determines whether unabsorbed sucrose is contributing to gas, bloating, or abdominal discomfort.

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    Urea Breath Test for H. pylori

    Non-radioactive 13C-urea method with ~95% sensitivity and specificity. Used for diagnosis or post-treatment confirmation of Helicobacter pylori infection; baseline and 15-minute collection.

    How It Works

    • 1 Order Kits

    • 2 Patients Complete the Test

    • 3 Lab Analysis & Results

    • 4 Clinical Interpretation

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    Step 1

    Order Kits

    Use the kits in-office or send home with your patient—no special equipment needed.

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    Step 2

    Patients Complete the Test

    Patients collect baseline and timed breath samples following the enclosed step-by-step instructions.

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    Step 3

    Lab Analysis & Results

    Samples are returned using the prepaid mailer provided in each kit. All samples are analyzed the same day they arrive in our lab. 

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    Step 4

    Clinical Interpretation

    Results are delivered by fax or email within 24 hours of receipt—ready for inclusion in your patient’s chart or treatment plan.

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    Practice Pays for Kits

    $219.00 (urea breath test) and/or $209.00 (hydrogen breath test), including free shipping.

    Price includes: kit, prepaid return mailer, laboratory analysis, and report.

    No additional costs.

    Payment is required when placing the order. 

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    Patient Pays for Kits

    We can set up your account so patients order directly using your name and account.

    Patient charge: $219.00 or $209.00 (includes free shipping).

    Patients receive a receipt for insurance submission.

    Your practice is supplied with customized order forms to assist with ordering. 

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    Kits Provided
    Free of Charge

    Kits may be provided at no cost if you expect to be a high-volume user.

    Medical Doctors (MDs) and other professionals who routinely submit lab work for insurance reimbursement may qualify. 


    Call 866-302-1998 (Mon–Fri, 7:30 AM – 6:00 PM EST) to discuss eligibility. 

     

    Bring GI Breath Testing Into Your Practice

    Metabolic Solutions makes it simple to add validated hydrogen/methane and urea breath testing to your diagnostic workflow. Our team supports your setup, training, and patient process every step of the way.

                               

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    Frequently Asked Questions

    Do I need to purchase any equipment?

    No. All test kits are complete and ready to use—there is no equipment to purchase and no financial commitment required.

    How are breath samples returned to the lab?

    Each kit includes a prepaid, preaddressed mailer. After collection, simply seal the box and drop it in any U.S. mailbox.

    Are results reliable?

    Yes. All assays have been validated to Clinical Laboratory Standards Institute (CLSI) guidelines.

    Can I use the kits in-office or send them home with patients?

    Either option works. Kits can be administered in your office by staff or sent home with patients for self-collection following the included instructions.

    Do you measure both hydrogen and methane gases?

    Yes. All hydrogen breath tests measure hydrogen and methane gases, with CO₂ included as a quality control indicator.

    What is the accuracy of the urea breath test for H. pylori?

    The ¹³C-urea breath test has approximately 95% sensitivity and specificity for detecting active H. pylori infection. The average accuracy of hydrogen breath tests is 85%.

    Are the breath samples stable and for how long?

    Yes, we have demonstrated stability up to 21 days in our collection device.

    Can children be tested?

    Yes, children can be tested if they are able to follow simple breath collection instructions. For those under 50 pounds, a modified dose is included in the kit instructions.

    Can you bill insurance?

    For practices that qualify, we can supply kits at no charge and bill insurance directly. For other arrangements, we provide receipts for patient reimbursement.

    Are results confidential?

    Yes. All results and patient data are handled in compliance with HIPAA standards. Only the ordering provider and patient receive results.

    Can multiple tests be done in one day?

    No. Only one test per day should be performed. However, patients may complete multiple tests on consecutive days if fasting and dietary requirements are followed.

    Laboratory Credentials

    • CLIA Certificate: 30D0970292
    • CA License: COS-90001393
    • NH License: 02731
    • NY License: 8098
    • PA License: 37608
    • Licensed in all 50 states
    • NPI: 1710985353
    • Medicare Provider Number: RE6176

    HIPAA Compliance

    As required by HIPAA, Metabolic Solutions safeguards all Protected Health Information (PHI):
    • PHI is not disclosed to unauthorized parties
    • Appropriate precautions are taken to prevent unauthorized use
    • Clients are promptly notified of any required disclosures
    • All internal PHI procedures and documentation are available for regulatory review

    Contact & Account Setup

    To set up a provider account or order kits, call:

    866-302-1998
    (Mon–Fri, 7:30 AM–6:00 PM EST)

    support@metsol.com

    Metabolic Solutions, Inc.
    460 Amherst Street,
    Nashua, NH 03063

    Contact Us

    Start Offering GI Breath Testing for Your Patients

    Metabolic Solutions provides validated hydrogen, methane, and urea GI breath tests. Fill out the form and our team will walk you through setup, pricing, and the most efficient workflow for your practice.

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