H. pylori infection and gastric cancer

H. pylori infection and gastric cancer

It is known that gastric cancer is strongly correlated with h. pylori infection, but the underlining cause was unclear. Researchers at Max-Planck Institute have confirmed that the gene activity in gastric cells exposed to H. pylori resembles the activity found in cancer cells. Furthermore, they identified that this happens because the genes responsible for repairing damaged DNA are down regulated in the presence of H. pylori. What is still unknown is why cancer develops in only 1% of the people infected with H. pylori. The best solution is early detection using urea breath test followed by eradication therapy.

Ref : http://www.eurekalert.org/pub_releases/2015-06/m-hpi061615.php